Kamusenene Education Center is located in Mubende district found in the Central Region of Uganda. The district covers an area of approximately 1,780 square miles.

The 1991 population census estimated the district population at about 277,500. In 2002 the national census estimated the population of the district to be about 423,450 people of whom (50.3%) were males and (49.7%) were female, with an annual population growth rate of 3.6%. It is estimated that in 2012, the population of the district was about 610,600.

The major economic activity in Mubende District is agriculture